BP506T

Systemic Pharmacology II (Theory)

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UNIT 1

Drugs Acting on the Central Nervous System General Anesthetics Halothane, Methoxyflurane, Enflurane, Sevoflurane, Isoflurane, Desflurane, Methohexital, Thiamylal, Thiopental, Ketamine, Ramelteon, Remimazolam, Fospropofol, Dexmedetomidine Sedatives and Hypnotics Barbital, Phenobarbital, Mephobarbital, Amobarbital, Butabarbital, Pentobarbital, Secobarbital, Chlordiazepoxide, Diazepam, Oxazepam, Chlorazepate, Lorazepam, Alprazolam, Zolpidem, Glutethimide, Meprobamate, Ethchlorvynol, Triclofos, Paraldehyde SAR of Barbiturates and Benzodiazepines Antipsychotics Promazine, Chlorpromazine, Triflupromazine, Thioridazine, Piperacetazine, Prochlorperazine, Trifluoperazine, Chlorprothixene, Thiothixene, Loxapine, Clozapine, Haloperidol, Droperidol, Risperidone, Molindone, Sulpiride, Brexpiprazole, Lumateperone, Pimavanserin, Samidorphan SAR of Phenothiazines Anticonvulsants Phenobarbitone, Methabarbital, Phenytoin, Mephenytoin, Ethotoin, Oxazolidinediones: Trimethadione, Paramethadione Succinimides: Phensuximide, Methsuximide, Ethosuximide Phenacemide, Carbamazepine, Clonazepam, Primidone, Valproic acid, Gabapentin, Felbamate, Perampanel, Lacosamide, Retigabine SAR of Anticonvulsants

UNIT 2

Anti-Infective Chemotherapeutic Agents Antitubercular Agents Isoniazid, Ethionamide, Ethambutol, Pyrazinamide, Para-amino salicylic acid, Rifampicin, Rifabutin, Cycloserine, Streptomycin, Capreomycin, Pretomanid, Clofazimine, Levofloxacin, Bedaquiline, Linezolid, Delamanid Antimalarials Quinine, Chloroquine, Amodiaquine, Primaquine, Pamaquine, Quinacrine, Mefloquine, Cycloguanil pamoate, Proguanil, Pyrimethamine, Artesunate, Artemether, Atovaquone SAR of Quinoline derivatives Antiprotozoals Metronidazole, Tinidazole, Ornidazole, Diloxanide, Iodoquinol, Pentamidine isethionate, Atovaquone,Eflornithine, Paromomycin, Nitazoxanide Antivirals Amantadine, Rimantadine, Idoxuridine, Acyclovir, Ganciclovir, Zidovudine, Didanosine, Zalcitabine, Lamivudine,Loviride, Delavirdine, Ribavirin, Saquinavir, Indinavir, Ritonavir, Valganciclovir, Peramivir, Lenacapavir Antifungals Amphotericin-B, Nystatin, Natamycin, Griseofulvin, Clotrimazole, Econazole, Butoconazole, Oxiconazole, Tioconazole, Miconazole, Ketoconazole, Terconazole, Itraconazole, Fluconazole, Naftifine, Tolnaftate, Posaconazole, Isavuconazole Anthelmintics Diethylcarbamazine, Thiabendazole, Mebendazole, Albendazole, Niclosamide, Oxamniquine, Praziquantel, Ivermectin Urinary Tract Anti-infective Agents Nalidixic acid, Norfloxacin, Enoxacin, Ciprofloxacin, Ofloxacin, Lomefloxacin, Sparfloxacin, Gatifloxacin, Furazolidone, Nitrofurantoin, Methenamine, Moxifloxacin SAR of Quinolones

UNIT 3

Antibiotics and Sulfa Drugs Antibiotics Penicillins, Cephalosporins, β-Lactamase inhibitors, Monobactams Aminoglycosides: Streptomycin, Neomycin, Kanamycin, Tetracyclines: Tetracycline, Oxytetracycline, Minocycline, Doxycycline, Macrolides: Erythromycin, Clarithromycin, Azithromycin Chloramphenicol, Clindamycin, Clavulanic acid SAR of Penicillins, Tetracyclines, and Cephalosporins Sulfa Drugs Sulphamethizole, Sulfisoxazole, Sulphapyridine, Sulphathiazole, Sulfacetamide, Sulphamethoxazole,Sulphadiazine, Mefenide, Sulfasalazine, Trimethoprim, Cotrimoxazole, Dapsone SAR of Sulfonamides

UNIT 4

Antineoplastic Agents Mechlorethamine, Cyclophosphamide, Melphalan, Chlorambucil, Busulfan, Thiotepa, Mercaptopurine, Thioguanine, Fluorouracil, Floxuridine, Cytarabine, Methotrexate, Azathioprine, Dactinomycin, Daunorubicin, Doxorubicin, Bleomycin, Etoposide, Vinblastine, Vincristine, Paclitaxel, Camptothecin, Cisplatin, Mitotane, Carboplatin

UNIT 5

Endocrine Drugs, Antidiabetic Agents and Narcotic Analgesics Endocrine Drugs Sex hormones: Testosterone, Nandrolone, Progesterone, Oestriol, Oestradiol, Oestrone, Diethylstilbestrol Drugs for erectile dysfunction: Sildenafil, Tadalafil Oral contraceptives: Mifepristone, Norgestrel, Levonorgestrel Corticosteroids: Cortisone, Hydrocortisone, Prednisolone, Betamethasone, Dexamethasone Thyroid and antithyroid drugs: L-Thyroxine, L-Thyronine, Propylthiouracil, Methimazole Antidiabetic Agents Insulin and preparations, Tolbutamide, Chlorpropamide, Glipizide, Glimepiride Biguanides: Metformin Thiazolidinediones: Pioglitazone, Rosiglitazone Repaglinide, Nateglinide, Acarbose, Voglibose Narcotic Analgesics Morphine, Codeine, Meperidine, Anilerdine, Diphenoxylate, Loperamide, Fentanyl, Methadone, Propoxyphene, Pentazocine, Levorphanol Nalorphine, Levallorphan, Naloxone SAR of Morphine analogues