BP704T

Modern Analytical Techniques (Theory)

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UNIT 1

General Introduction to Herbal Industries, institutions and trade status of herbals (a) Role of medicinal and aromatic plants trade in national economy of a country and introduction of Current trade status and potential of some commercially important medicinal plants/natural products like Ashwagandha, Turmeric, Ginseng, Amla and essential oils. (b) A brief account of bioeconomy, biodiversity hot spots and plant- based industries and institutions involved in research work on medicinal and aromatic plants in India. (c) Emerging therapeutic categories of Herbal Medicinal Products available in market, their composition with rationale for Aphrodisiac, Antistress, anti-diabetics, antihyperlipidemic, immunomodulator, hepatoprotective and kidney disorders (d) Emerging Herbal cosmeceuticals: Anti-Aging, Depigmenting, anti- acne, sunscreen, detoxifying, anti-irritant, nutricosmetics.

UNIT 2

Commercial Production and Standardization of botanicals Significance of AYUSH/ WHO-GMP, GLP and USFDA compliant facility in production of quality herbal products. Commercial production of standardized herbal extracts with clinical relevance: Coleus, Amla, Turmeric, Ashwagandha and Senna. Commercial production and standardization of volatile oils: Eucalyptus oils, Lavender oil and Peppermint oil, Rosemary oil Preparation and standardization of Ayush formulations viz Aristas and Asawas, Ghutika/Habb, Churna/ Shafoof Arq, Sharbat, Tincture and Bhasma.

UNIT 3

Modern methods of analysis of Plants and Plant-based products Basic principles and applications in analysis of botanicals: Spectroscopic methods: UV-Visible spectroscopy, IR Spectroscopy, NMR spectroscopy and Mass spectroscopy, Atomic Absorption Scpectroscopy Chromatographic methods: HPTLC, HPLC, UPLC, GC,

UNIT 4

Isolation, Characterization, Commercial Production and analysis of bioactive phytoconstituents Isolation, characterization with commercial production, identification and analysis of bioactive phytoconstituents: Artemisinin, Sennosides, Withanolids, Boswellic acid, Atropine, and Lycopene.

UNIT 5

International Regulatory Perspectives (a) Overview of global regulations for herbal products (e.g., World 07 Hours Health Organization, United States Food and Drug Administration – Dietary Supplement Health and Education Act, European Medicines Agency, TGA-ARG Therapeutic Goods Administration – Australian Regulatory Guidelines for Complementary Medicines, Natural Health Products (Canada) (b) Harmonization challenges and mutual recognition of traditional medicine (c) Importance of safety, efficacy and pharmacovigilance in herbal product regulation (d) Study of Monographs on herbal drugs and botanicals related to Indian Pharmacopoeia, United States Pharmacopoeia Herbal Medicine and Dietary Supplement, Ayurvedic Pharmacopoeia of India and Unani Pharmacopoeia of India.